Has there been any improvement if so how long after did it take ? The vets and neurologists say it's not simparica trio - but she was perfectly healthy until that dose was given. In addition to killing fleas and several kinds of ticks, Simparicais effective in preventing and treating mange and ear mites. She had been on the Seresto collar and Tri-Heart for 8 years with no issues. Moxidectin was first approved by the FDA in 1997 for the prevention of heartworm disease in dogs. No way I will ever give it to her again. Any believers out there please say a prayer for our pup as I will for the people on this thread. Simparica TRIO requires a prescription from your veterinarian. This stuff should be banned. Same here! Compared to other products, the efficiency of this . She had some itching and a bit lethargic but is eating very well. I should have know it was a sign when he spat it out. I have a person that bought a husky puppy from me March 6 @ 6 weeks old. He also got that odd cough here and there that I read someone else mention. About 2 weeks later he had tremors, drooling, lethargic, uncoordinated, vomiting and was touch and go for a couple days. A dog fence is an important detail to consider when adopting a pet for the first time or moving your dog to a new home. Best of luck. Possible side effects: Vomiting, diarrhea (if these . I have noticed that he hardly needs no meds for this neurological issue near the end of the month. Simparica Trio reduced live flea counts, as well as clinical signs of FAD, by 99.0% at day 30 and by 99.7% at day 60. 98. What Are The Side Effects Of Simparica Trio For Dogs? They keep telling me that she would have been sick from the first pill, not just the 2nd. My vet recommended this for my Scooby he justed turned 8 on July 4 and had to take him to vet because of fleas since Monday when he got his first treatment of simparica he's been momping around the house and not eating his food. I need to tell my vet to switch! How long did these symptoms last? Simparica Trio is considered safe for dogs as young as eight weeks old who weigh at least 2.8 pounds. I immediately filed a case number with Zoetis and informed my Vet as well as current Vet hospital he is being held at. Benefits: Each tablet provides a full month of protection against fleas and ticks. Simparica is approved for dogs and puppies weighing more than 2.8 pounds and over 6 months of age. Thank you for this. I started thinking about his history. Some adverse reactions to Simparica include tremors, decreased awareness of body movement, loss of control over bodily movements, problems blinking, and/or seizures. for flea and ticks? Something I will never know what happened to herIf I knew this would kill her I would never had used it. Sarolaner is also used in combination products for both dogs and cats. Buddy 8 year old male Boxer formerly energetic and playful. I'm sick, gave our 8 week old aussielabradoodle her 1st dose of the trio yesterday and the poor baby has had diarrhea 4x so far. Hes been on it for six months. Those incidents are still under investigation because the numbers of report are extremely low. I took him back to the vet and explained my concern that it was from the Simparica Trio and they didn't seem concerned that it was the issue. I will be changing clinics immediately. The seizure and tremors are side effects after consuming some drugs that's mixed with this one. I pray for my baby to be ok and all of you who are in this battle. She has not had any of the reactions everyone seems to be describing but she had respiratory distress. She uses drops 4 times a year on the top of the neck for fleas etc and told me to address the heart worm problem with the vet. Humans are another matter. Vet thinks it may be Addision disease and wants to test for it. No more of this poison for him. The reaction lasted less than 12 hours. I'll be calling them tomorrow. The Vet's are so busy that even if you can get in you don't get anywhere. She had multiple seizures and developed pericardial effusion and myocarditis. I used to use revolution but they dont cover ticks as well. My last one lived to almost 15yrs old and I truly believe it was because I had him on Springtime Garlic tabs. I give my dogs Simparica at the beginning of each month. Wednesday morning at 5am she awoke with bloody diarrhea and it turned into just blood. He just couldn't stand good, he constantly shakes his head. Vet says not to go back to Any brand oral flea/tick meds, so well be using Frontline drops on her shoulders from now on. old . I sure hope he makes it! The only thing in his diet that really changed was his flea, tick and heartworm protection. Reading all these similar cases cant figure out how the hell this crap is still being prescribed. I thought it was just her aging but now I think it al started when she started this medication. While she has not had seizures, trembling, or spasms, sometimes she just squeals and jumps up for no obvious reason. PetMDs medications content was written and reviewed by veterinary professionals to answer your most common questions about how medications function, their side effects, and what species they are prescribed for. Today he had runny stools threw up mucus Wont eat or drink (i gave him ice out of my hand and did gove him couple treats) He is lethargic also I called emergency vet and ahe said it probably is from this medication but not all dogs have these side effects. Hi Chelsea, I am hopeful that your Shepherd has recovered. We are experiencing the same thing. We administered the first dose on Wednesday June 1st to our 9 year old bouvier flanders. But today, after he ate dinner and drank water, it all came back up. Can you tell me if your dog is back to normal now?!?! Are there any side effects to Simparica Trio? Please do not use this drug. Sarolaner (brand name Simparica) is used to treat and control flea and tick infestations in dogs. He seems dehydrated. If it has been a long period of time since the last dose was given, you may see fleas temporarily during the missed time. I do believe it caused her blindness. Now his tail looks like a rat tail. I'll be spreading the word. Is there hope? She seems to be feeling better but still very concerned of why these levels are still up. I'm so scared. Its Sunday night and still vomiting. Sarolaner is effective against the following tick species: Moxidectin is an antiparasitic drug in the macrocyclic lactone class. He was diagnosed with "Sundowners" . My sweet, funny, smart as can be baby girl died on 9/26/20. Started giving my dogs Simparica Trio 5 months ago didn't put together the changes in the one dogs personality until today within a couple of weeks she would all of a sudden go from a loving dog to attacking the other dog it is getting worse. Eat grass and vomit. and to only let him out on a leash to go potty. But anyways - the other night , his feet collapsed from under him & he fainted . We think that the drug is the cause of the seizures . The initial trial had seizure results but supposedly only in dogs with seizure history. After reading all your entries, i'm thrilled i chose to take her off of it. 24 hours later she had another one. To report suspected adverse drug events for these products and/or obtain a copy of the Safety Data Sheet (SDS) or for technical assistance, contact the appropriate manufacturers at the following phone numbers: Merck Animal Health (Bravecto): 800-224-5318, Elanco Animal Health (Credelio): 888-545-5973, Boehringer Ingelheim (Nexgard): 888-637-4251, Zoetis (Simparica, Revolution Plus): 888-963-8471, If you prefer to report directly to the FDA, or want additional information about adverse drug experience reporting for animal drugs, see, Pet owners and veterinarians who have additional questions can contact. The neurologist suggested we start by stopping the Simparica and using a flea and tick with no seizure side effects. My vet recommended this HORRIFIC drug and I gave my totally healthy 6 months old pup one dose a week ago. I feel so bad ,my 8weeks cockerspaniel hasnt been the same 24 hours of giving first dose of Simparica trio.My boy has been distressed with lethargic conditions,sleepy and peeing . I gave the 1st one to my dog, 1st of this month. Simparica and Simparica Trio should be stored at or below 86 F. Brief exposure of Simparica to temperatures up to 104 F are acceptable. Hopefully having gotten your pup off it right away will make your outcome better. We rushed to the vets who said it had to be neurological and once I mentioned the diarrhea she looked into Simparica suspecting MDR1 with my dog. Still waiting on the vet and waiting to talk to ASPCA poison control. It is the most convenient flea and tick protection product on the market. She will not get this anymore. I am also going to contact the vet who gave it to me and tell him all this stuff. I made some chicken and rice. its only been about 4 days since and its been a steady decline. After about 2.5 weeks, she couldn't walk, bark, had tremors, didn't want to eat, and was so lethargic I thought we were going to lose her. After your dog takes the chew, the drugs circulate in the blood, and when a flea or tick bites your dog, it's exposed to the chemical. Do not give extra or double doses. Im petrified after reading the comments here. It kills heartworm larvae by causing paralysis that leads to the death of the parasite. Very small sample - many deformities, stillborn. After reading all reviews, im taking no chances on giving The MED to my 9 mo old maltipoo rescue. Although he didnt continue throwing up and was fine otherwise, he was still outside 12 hours later eating grass. My precious rescue has been sick twice, currently on her second episode. (My first warning sign right there). But I noticed that I had to "wake him' several times in only 2 minutes time, but he wasn't sleeping, his eyes were open and I saw them rolling in the back of his head! My 15 yr old doodle wasnt given bravecto because of reviews. I just gave my Matty her first dose. Simparica Trio is a veterinary medicine used to treat dogs with flea or tick infestations and roundworm or hookworm infections in the gut. AVOID THIS PILL! This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. If she had just taken it they could give her Charcoal. We rushed him to the emergency vet and they put him on keppra to stop the seizures. She has been on it for 6 months. For Instance he has never liked grooming, I brushed him out last night and he slept through the whole thing. So the next day was Saturday , me & my husband got up early . I'm besides myself. I guarantee he will not take this trash again. What are the side effects of Simparica trio for dogs? She became extremely lethargic and feverish so we rushed her to Hospital. Her blood work came back fine. Thanks all for sharing your experiences. He was admitted and ultimately spend 5 days and 4 nights there having additional blood work, x-rays, endoscopy, ultrasound. My one year old has severe diarrhea and is very agitated and anxious. You don't think I'm going to continue with this poison. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. I gave my yellow Lab, Sophie, her first Simperica trio. At first B seemed fine. None of our pets did they were healthy. He has been very healthy, and it does not seem to bother him, but it is becoming more noticeable recently. I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. Only some dogs show this symptom. It really helped us to put this diarrhea condition in perspective. My baby is so sick from this Drug. Poor baby has had vomiting and diarrhoea ever since. Can my dog still get Lyme disease from a tick that was in him. Drinking water and peeing excessively. This morning (12/19/21) was a bit better, still hesitant on the steps but we didnt experience any loss of appetite and was eager to go outside (still some diarrhea though). She has been very unpredictable and snapping at people but this is improving. This was the 2nd does I have him. I gave my 1 year old collie cross Simparica flea and tick medication. (145 Reviews) $15.50 - $31.09. Work up from the neurologist shows all his tests came back negative. Bentlee has been fine for 12 + hours in the house while I was stuck at work and never a drop of anything in the house. (Ours never did, she died 4 months later.) I would notice he gets super tired walking and would go limp in my arms. now seizures daily on all sorts of meds for it and the cost with medications to try and control seizures and vet visits and mainly seeing my once healthy playful full of life pups having seizures daily even in her sleep breaks my damn heart !!!!!!!!!!!!!! I've beaten myself up so much giving her this drug, I felt I could trust the vet and the drug company but we obviously cant and it's all about making more money. I'm so upset. But im 99% sure the simparica is what caused it. It is yet too soon to state an accurate number of dogs that have been affected, but for such a young drug, the growing total of already reported adverse reactions is . I took her home. Gave my 3 year old Yorkie Simparica and 24hrs later he became hyperactive panting pacing and started hiding in dark places. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. Each month he got sicker and sicker. If you need to get rid of parasites, spot-on (the one by a German company is effective enough) will do the job and do it safely. This is because it doesn't kill adult heartworms. He also lashes at me with his teeth. Did anyone see any signs of improvement in their dogs? She had right sided weakness, with right sided neglect( the inability to process stimuli with impaired spatial recognition ). Nothing. Im praying over him too . And since then has had diarrhea and loose poop. I knew it was bad from the onset but the vet said I can't take a chance on him getting heartworms because the mosquitos are so bad not to mention fleas and ticks. The most common side effects of Simparica in dogs are vomiting and diarrhea. We asked our vet, but he ignored the question. Somedays he will have 2 and then he will go for a couple days without having any issues. Heres what you need to know about why cats purr and what your cat may be telling you when her motor is running. My 11 year old mini Aussie has been taking Simparica 1.5 years. She's finally resting at home, but still not able to walk, run, eat, etc. Today the seizure like attack happened even though he is on the steroids. X-rays fine. and now i'm on an hour by hour let's see if she will perk up. Generally, they may instruct you to administer it immediately when you remember and resume monthly dosing. However, these adverse effects are rarely observed in pets and overall the product is proven to be suitable for all dogs without occurrence of any side effects. Then she lost control of her legs and couldn't walk or stand. A heartworm test may be necessary in about six months (that's how long it takes heartworm larvae to mature enough to show up on a test). Simparica Trio can be administered to your dog at any age, but it's best to start treating your dog one month before the fleas become active. The active ingredient of Simparica, sarolaner, belongs to a newer class of flea and tick preventatives called isoxazolines. But now I'm almost convinced that they could have been seizures, and I just pray that they weren't, and pray that he doesn't have to experience anymore troubles. Kristine, unfortunately my sweet Dolly passed away on October 9th. CET HEXtra Chews. He walked outside peed then tried to come back in the house but his legs gave out . Today started diarrhea & he has gone 5 times so far while not eating much. Friday early evening Bellas stool was still soft with structure with the outside color almost black but the inside was tinged with lime green. Im done with this drug! But I have heard of other dogs who recover, or who continue having seizures but not fatal. Charlie took the pill on Monday and could not even walk this morning. 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At least 2.8 pounds and over 6 months old pup one dose week. She lost control of her legs and could n't stand good, constantly...
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