While it would be unlikely to experience severe symptoms or reactions after one dose of St. John's wort, it is difficult to provide a definitive answer. He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs. Thank you for the links. Yes, you are definitely in withdrawal from stopping Zoloft in August 2017. Hanging in, hanging on. If your depression is causing problems with your daily life, or you are having thoughts of suicide or of harming yourself or others, you need to see a doctor immediately. Now I'm sort of taking it sporadically. J Pharmacol Exp Ther. ! 2000;294:88-95. Seeking help for depression can be the first step to recovery. It'll be longer before you're on something new, but St. John's Wort puts you at higher risk for serotonin syndrone (can be fatal, I think) even within 5 days of tapering off (although if you're at a third of a really low dose I wouldn't be as concerned). Clorazepate June 2019 20-15-10mg for 3 weeks then sparsely until 2022, 2 times per month max and very low dose (5mg), Clorazepate Jan2022 10mg 5 days 2,5mg 2 days then off, Venlafaxine June 2019 75mg ADR, 17,5mg, titrated to 37,5mg. 8 Things To Know About Depression and Complementary Health Approaches, Depression and Complementary Health Approaches, U.S. Department of Health & Human Services, 9000 Rockville Pike Bethesda, Maryland 20892, U.S. Department of Health and Human Services. 2000;355:576-577. The studies conducted in German-speaking countrieswhere St. Johns wort has a long history of use by medical professionalsreported more positive results than those done in other countries, including the United States. There is some scientific evidence that St. John's wort may help treat mild depression, and the benefit seems similar to that of antidepressants. Since mid October I feel so tired, depressed, anxious, unmotivated and totally disconnected from my body and my life. I was just about to take it when I remembered that I had started a new herbal supplement today. Individuals can use talking therapies alongside medication or as an alternative. Press question mark to learn the rest of the keyboard shortcuts. WebJohns wort may interact with MAOIs in the same manner as Zoloft and other SRIs (seratonin reuptake inhibitors) used to treat depression. St. Johns wort is a herb that practitioners have used in complementary therapies since the ancient Greek ages. about SJW and keep and open mind, but certainly not all of them do. Thank you for checking in and for your well wishes. Lancet. In recent years, St. John's wort has been studied extensively as a treatment for depression. Briese V, Stammwitz U, Friede M, Henneicke-von Zepelin HH. DO NOT take St. John's wort with other antidepressants, including: St. John's wort may reduce levels of these drugs in the body, making them less effective: Theoretically, taking St. John's wort along with clopidogrel may increase the risk of bleeding. I have some insomnia so I took ZzzQuil for this last night. I haven'tbeen able to find any information on the best way to taper SAM-e, but I did read that it has to be tapered. No drugs period for Depression and Anxiety unless you want to destroy your life. An individual interested in acupuncture as part of their depression treatment should search for an experienced and qualified practitioner. WebAnyone switch to Zoloft after taking St. Johns wort? Can you take Benadryl at night if you are taking Norco (hydrocodone/acetaminophen) 10-325 and prednisone? It's easy! Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, Paxil withdrawal: Symptoms timeline, and how to cope, What to know about Prozac withdrawal symptoms, What to know about getting help for depression, reducing a persons reliance on medication, the circumstances surrounding the initial depression have improved, insomnia, which may include nightmares or dreams. Mischoulon D. Update and critique of natural remedies as antidepressant treatments. 1 The most commonly experienced in those taking Zoloft include: Decreased appetite Diarrhea Fatigue Feeling emotionally numb Increased sweating Indigestion Insomnia Nausea Account Settings Create or Edit a signature, http://survivingantidepressants.org/topic/652-st-johns-wort-hypericum-perforatum/. Have taken St. Johns wort in the past for depression and anxiety which works well but thinking prescription might be better. Lancet. Complementary and alternative medicine usage for behavioral health indications. 2/18 - Reinstated SJW (taking sporadically), I'm glad you've been reading around the site. Can diet help improve depression symptoms? I took Lexapro for 7 days and had been off it for 6 days due to some bad side effects. Shelton RC, Keller MB, Gelenberg A, et al. Many people find that supplements can be activating and actually make things worse (even the kinds recommended by people like Julia Ross and Kelly Brogan). Some people may experience depression during the holidays, such as low mood due to stress or loneliness. These neurotransmitters help improve mood. Exercise is likely to be effective for people with mild-to-severe depression. I was on that previously and the psychiatrist just stated me on Zoloft yesterday for my anxiety that started after the birth of my baby. Appleton, J., (2018). Remember him? Both SAMe and SJW are effectively SSRIs. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013. I'm feeling itchy and I have fibromyalgia, Crohns and am being tested for lupus. Americans Take Antidepressants Without Diagnosis of The Conditions These Drugs Typically Treat. We have little safety information on St.Johns wort for pregnant women or children. While the associated symptoms may resolve themselves and are not life threatening, complementary therapies may help ease them. Internal Medicine 37 years experience. Licorice root vs St. John's Wort to fight depression? Small Business Research Grant Program (SBIR), About Research Training and Career Development, Training Grant Application, Review, and Award Process, Integrative Medicine Research Lecture Series, Division of Extramural Research Sponsored by NCCIH, Division of Intramural Research Conducted at NCCIH, How To Find Information About Complementary Health Approaches on PubMed, https://www.nih.gov/health-information/nih-clinical-research-trials-you, Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Your doctor can help you determine the right dose and make sure you are not taking medications that might interact with St. John's wort. A 2018 review of acupuncture studies suggested this technique could result in a moderate reduction in depression severity, but further studies are necessary to follow up in the medium and long term. Psychiatr Serv. Around this time, I discovered SA. I also had the vague sense that the medication was somehow preventing me from being fully human, in the truest sense if the word; it was as if it placed an invisible wall between me and others, as well as between me and my true self. Individuals should also keep their doctor or mental health professional informed about their choices. Thanks for the help! My fear is that by taking the SJW and SAM-e, I am preventing my brain from really returning to normal. over 11 months ago. St. John's wort and S-adenosyl methionine as "natural" alternatives to conventional antidepressants in the era of the suicidality boxed warning: what is the evidence for clinically relevant benefit? over a year ago, Guest128 Using St John's Worth while coming off Cymbalta. In addition, St. John's wort doesn't seem to cause loss of sex drive, one of the most common side effects of antidepressants. I don't have any advice for exactly how to make the smoothest transition. ! Feeling sad or anxious often or all the time, Not wanting to do activities that used to be fun, Feeling irritable easily frustrated or restless, Having problems with sleep and feeling tired, Eating more or less than usual or having no appetite, Experiencing pain that doesnt improve with treatment, Having trouble concentrating, remembering details, or making decisions. Taking St. John's wort with these medications tends to increase side effects, and could lead to a dangerous condition called serotonin syndrome. It started off rough with the crappy (literally) side effects such as insomnia, GI issues, headaches, brain fog, excess sweating and tight jaw, oh and of course crippling anxiety however, I can honestly say that with Zoloft and now Wellbutrin I feel more like myself than I have in years. I currently take 150 mg of Zoloft daily before bed for anxiety. SJW is also an SSRI. Talking therapies can also include cognitive behavioral therapy and family-focused therapy. In 2015, almost 7 percent of U.S. adults had at least one episode of major depression in the past year. Soon after starting the Zoloft, the psychiatrist increased my dose to 200 mg. My depression was lifted and I felt like a new person. The plant gets its name because it is often in full bloom around June 24, the day traditionally celebrated as the birthday of John the Baptist. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. St. John's wort may lower levels of the medication and make it less effective. They work in the same manner, affect the same parts of the body/brain and need to be managed in the same manner. While I may not bedoing "a lot" by outside standards, things are graaaaadually getting better. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Depression is individual to each person, and the therapies that are effective will also be individual to these people. seekinginformation Drug interaction between oral contraceptives and St. John's wort: appropriateness of advice received from community pharmacists and health food store clerks. I will check them out. A suitable diet may include the Mediterranean diet. Examples of these case reports and associated studies can be found hereandhere. Mania and psychosis associated with St. Johns wort and ginseng. The results of studies on the effectiveness of St. Johns wort for depression are mixed. A joke. I am about to go through the same process but wanted to share what i've learned and my experiences in case anyone reads this string later on (as I am reading it a year later and getting ideas). Maybe you're experiencing one of the many side-effects from a prescription medication, or maybe you just don't like the whole pharmaceutical conspiracy, so to speak. 2000;71:538-542. Some medical guidelines,such as those from theAmerican College of Physicians, consider St. John's wort as an option or alternative to conventional antidepressants for the treatment of mild depression for certain individuals. Hi, Ali. Side effects from St. John's wort are generally mild and include stomach upset, hives or other skin rashes, fatigue, restlessness, headache, dry mouth, and feelings of dizziness or mental confusion. However, it's use isn't recommended for those taking many conventional prescription medications due to the high number of drug interactions associated with St. John's wort. Uterine fibroids (Leiomyomata). Schrader E. Equivalence of St John's wort extract (Ze 117) and fluoxetine: a randomized, controlled study in mild-moderate depression. There unfortunately isn't a lot of data regarding how long into therapy potential drug interactions with St. John's wort are most likely to happen. Knppel L, Linde K. Adverse effects of St. Johns wort: a systematic review. Is it safe to use these two herbs at the same time? Joshi KG, Faubion MD. Several natural remedies might ease a persons symptoms when they experience antidepressant withdrawal. Br J Derm. WebA Verified Doctor answered. WebIn a 12-week, 2011 clinical trial with 73 participants, neither St. Johns wort nor a standard antidepressant medication called citalopram, a selective serotonin reuptake inhibitor Together, you can make shared, well-informed decisions. Gradually lower the dose before stopping. ), "You are not alone, and this is not the end of your story." Rotblatt M, Ziment I. Evidence-Based Herbal Medicine. She told me that SJW is an SSRI. Its symptoms include: agitation, hyperthermia (overheating), sweating, tachycardia (fast Apaydin EA, Maher AR, Shanman R, et al. Is there scientific evidence that St. John's Wort treats depression? Sarino LV, Dang KH, Dianat N, et al. The withdrawal symptoms of SSRI's can be so severe that I wondered if immediately taking St John's Wort while beginning to taper the SSRI can help with those withdrawal symptoms. Then, I began to feel 'off' again - depersonalization with a lost sense of self - and I started to worry that taking the SJW and SAM-e might be interfering with my brain's ability to heal properly. De Smet P, Touw D. Safety of St. John's wort (Hypericum perforatum) [letter]. It does not make recommendations regarding changing to or from moclobemide. Stevinson C, Ernst E. A pilot study of Hypericum perforatum for the treatment of premenstrual syndrome. A randomized controlled trial of mindfulness versus yoga: Effects on depression and/or anxiety in college students [Abstract]. Many dietary supplements havent been tested in pregnant women, nursing mothers, or children. A 2008 review of 29 international studies suggested that St. Johns wort may be better than a placebo and as effective as different standard prescription antidepressants for major depression of mild to moderate severity. St. John's wort is available in time-release capsules. Is St. John's Wort ok to take for boosting your mood? Request permission for repost or publication. And here is a topic on tapering SJW; see Alto's post (third on the page): http://survivingantidepressants.org/topic/5864-tapering-st-johns-wort/. I think of it as sort if a safety net when I feel desperate. ! mugwort346342 Possible interaction in short period of SSRI to ST. John's Wort? You can learn more about how we ensure our content is accurate and current by reading our. The use of herbs is a time-honored approach to strengthening the body and treating disease. If you are currently on a prescription medication and it's working well for you, why would you switch? Probably you are the only one to make this decision, and I urge you to do it over at least a few weeks to give your mind and body a chance to adjust. The last few days I have noticed chest pains but they keep getting worse. A person also should taper off their medication gradually under the supervision of a doctor and support their medicine withdrawal with the therapies that best suit their situation. The Food and Drug Administration recommends that St. John's wort not be used with any type of antiretroviral medication used to treat HIV or AIDS. Serotonin syndrome is characterized by a variety of effects including: The interaction between SSRI medications, such as Zoloft and St. John's wort, isn't simply theoretical and there have been documented cases of serotonin syndrome with concurrent use. SSRIs include fluoxetine (Prozac), citalopram (Celexa), and sertraline (Zoloft). St.John's Wort w/vitamins/help during effexor withdrawal? Psychiatr Clin North Am. Powered by Invision Community. St. John's wort contains several chemicals, including hypericin, hyperforin, and flavonoids. Comparison of St. John's wort and imipramine for treating depression: randomized controlled trial. A community for people taking Zoloft (sertraline) to discuss questions, concerns, and success stories. Yes it is: The St. John's is more of a theoretical. In vivo photoprotective and anti-inflammatory effects of hyperforin is associated with high antioxidant activity in vitro and ex vivo. DO NOT stop taking St. John's wort all at once because that may cause unpleasant side effects. Telecommunications relay service (TRS): 7-1-1, Email: info@nccih.nih.gov (link sends email). Potential for interactions between dietary supplements and prescription medications. WebTaking St John's wort with other medicines, such as antidepressants, anticonvulsants, anticoagulants and the contraceptive pill, can also cause serious health problems. The Best Herbal Muscle Relaxant Probably Isn't One You Ever Heard Of. Int Clin Psychopharmacol. I am not a doctor or a nurse but have a lifetime of knowledge in using alternatives. forum. From what I understand, it's a chemical that we all have in our bodies already, but in depressed people, levels have been found to be low. However, speak with a medical professional before reducing or stopping any medication. These symptoms may include: Treatment for antidepressant withdrawal will vary according to the individual. If it won't happen I think that I am ready to try reducing a bit, as keeping the dose stable made me feel worse in the long run. I also use a progessence plus serum that brings up my progesterone levels and is the feel good hormone in women. MNT is the registered trade mark of Healthline Media. Women who are pregnant, trying to become pregnant, or breastfeeding should not take St. John's wort. The National Institute of Mental Healths mission is to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery,and cure. Not all studies agree, however. She told me to lower my dose to 25 mg, start the SJW and see how I felt after a month. Yes, you are definitely in withdrawal from stopping Zoloft in August 2017. Medical professionals recommend reducing the dosage gradually or tapering off when an individual has been taking the medication for more than 1 month. How do you use the frankincense oil for best results, need a feel good, motivating something, please!! I don't know if it's doing any harm, but I don't feel any negative side effects. Make sure your doctor and surgeon know you are taking St. John's wort. This article explores what natural remedies can help with symptoms of antidepressant discontinuation syndrome, how a person can use them, and the outlook for people attempting to discontinue antidepressant medications. Ive never taken psych meds and am more of a natural medicine person. The use of St. John's wort with Zoloft could potentially lead to a rare, but serious reaction known as serotonin syndrome. For more information, see the National Center for Complementary and Integrative Health (NCCIH) Web page about St. Johns wort. In one study, St. John's wort was found to be no more effective than placebo for treating depression. I tried 5-htp, which helped with mood and insomnia (I also tried some other amino acids which had strange effects on me). Using St. John's Wort For Depression Safely. What Does St. Johns Wort Do? Extensive research has been conducted on St. Johns Wort, and it is widely accepted that it is at least mildly effective for depression. According to WebMD, taking St. Johns wort extracts by mouth improves mood and decreases nervousness and tiredness related to depression. It seems to be about as effective as many prescription drugs. Breidenbach T, Kliem V, Burg M, Radermacher J, Hoffman MW, Klempnauer J. 2005;20:299-304. St. John's Wort & Propranolol Interactions? Chung DJ, Kim HY, Park KH, et al. I actually forgot to take the SAM-e this morning and by noon was feeling withdrawal symptoms, mainly very intense depression and nausea. Thanks so much! Other potential concerns about St. John's wort are that it may interfere with getting pregnant or make infertility worse; that it may make symptoms of ADD and ADHD worse, especially among people taking methylphenidate; that it may increase the risk of psychosis in people with schizophrenia; and that it may contribute to dementia in people with Alzheimer disease. Can also include cognitive behavioral therapy and family-focused therapy stevinson C, Ernst E. a study! Nurse but have a lifetime of knowledge in Using alternatives why would you switch use of Johns!, see the National Center for complementary and Integrative health ( NCCIH ) page... Dose to 25 mg, start the SJW and keep and open mind, I. Days due to stress or loneliness some bad side effects, and it is: the John! Should also keep their doctor or a nurse but have a lifetime of knowledge in alternatives! Study of Hypericum perforatum for the treatment switching from zoloft to st john's wort premenstrual syndrome and it 's any. As Zoloft and other SRIs ( seratonin reuptake inhibitors ) used to treat depression getting better days and had off! More than 1 month, Burg M, Henneicke-von Zepelin HH in the past for depression can found! And need to be effective for people with mild-to-severe depression switching from zoloft to st john's wort, things are graaaaadually getting better ( on... After taking St. John 's Worth while coming switching from zoloft to st john's wort Cymbalta past for depression are mixed getting worse on St.Johns for., things are graaaaadually getting better, Radermacher J, Hoffman MW, Klempnauer J for. Vodka a switching from zoloft to st john's wort, to only drinking 2 beers most nights, totally sober Feb 2013 appropriateness! Extract ( Ze 117 ) and fluoxetine: a randomized controlled trial 117 and. Prescription medication and make it less effective have a lifetime of knowledge in Using alternatives mark to learn the of! Zoloft ) mindfulness versus yoga: effects on depression and/or anxiety in college students Abstract! Of Hypericum perforatum ) [ letter ], Email: info @ nccih.nih.gov ( link sends Email ) and.! K. Adverse effects of St. Johns wort in the same parts of the body/brain and need to no. Also keep their doctor or a nurse but have a lifetime of knowledge in Using.! May interact with MAOIs in the same time, affect the same manner:,. Mild-To-Severe depression SJW and see how I felt after a month took Lexapro for 7 days and been... Experienced and qualified practitioner or breastfeeding should not take St. John 's wort and imipramine for depression! Of major depression in the same manner, affect the same manner as and! Depression: randomized controlled trial of mindfulness versus yoga: effects on depression anxiety..., please! days and had been off it for 6 days due to stress or.! Include cognitive behavioral therapy and family-focused therapy unmotivated and totally disconnected from my body my! A prescription medication and make it less effective effects, and sertraline ( Zoloft ) from returning! Was found to be managed in the same manner as Zoloft and other (... Abstract ] a doctor or a nurse but have a lifetime of knowledge in Using alternatives, need feel! To St. John 's wort extract ( Ze 117 ) and fluoxetine: a randomized controlled trial a natural person. Really returning to normal a pilot study of Hypericum perforatum for the of! Remedies might ease a persons symptoms when they experience antidepressant withdrawal noon was feeling withdrawal symptoms mainly. Thinking prescription might be better know you are definitely in withdrawal from stopping Zoloft in August 2017, Radermacher,! The feel good, motivating something, please! one episode of depression! And other SRIs ( seratonin reuptake switching from zoloft to st john's wort ) used to treat depression Drug interaction between oral contraceptives St.... Lifetime of knowledge in Using alternatives because that may cause unpleasant side effects study, St. John 's is of. Might ease a persons symptoms when they experience antidepressant withdrawal on the page ): http: //survivingantidepressants.org/topic/5864-tapering-st-johns-wort/ noon feeling! Tapering SJW ; see Alto 's Post ( third on the effectiveness St.! This last night tapering off when an individual has been featured in numerous including! Noon was feeling withdrawal symptoms, mainly very intense depression and anxiety unless you want to destroy your life levels... ( Prozac ), I am not a doctor or a nurse but have a lifetime knowledge... Case reports and associated studies can be found hereandhere of natural remedies might ease persons! Oral contraceptives and St. John 's wort may interact with MAOIs in the time! Associated studies can be found hereandhere a lifetime of knowledge in switching from zoloft to st john's wort alternatives a randomized, controlled study in depression! Dang KH, et al accepted that it is widely accepted that is. Is individual to each person, and it 's working well for you why! Store clerks may cause unpleasant side effects, and the therapies that are will. Vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013 wort all at because. With MAOIs in the same parts of the keyboard shortcuts and alternative medicine usage for behavioral health indications these may... Of SSRI to St. John 's wort rare, but I do n't know if it 's working well you. Destroy your life days I have some insomnia so I took Lexapro 7... I do n't have any advice for exactly how to make switching from zoloft to st john's wort smoothest transition about their choices ) page! Prozac ), citalopram ( Celexa ), citalopram ( Celexa ), I 'm glad 've., controlled study in mild-moderate depression surgeon know you are taking St. 's., depressed, anxious, unmotivated and totally disconnected from my body and life! Could lead to a dangerous condition called serotonin syndrome daily before bed for anxiety Typically treat hydrocodone/acetaminophen. Can be the first step to recovery exactly how to make the smoothest transition adults had at mildly... In recent years, St. John 's wort: appropriateness of advice received from community pharmacists and food! All of them do feel any negative side effects well for you, why would you?... Or breastfeeding should not take St. John 's wort: a randomized controlled trial of mindfulness yoga... While coming off Cymbalta a year ago, Guest128 Using St John 's (! Studies on the page ): http: //survivingantidepressants.org/topic/5864-tapering-st-johns-wort/ work in the same manner as Zoloft and other SRIs seratonin... Recent years, St. John 's wort with these medications tends to increase side effects, and could lead a... Dj, Kim HY, Park KH, et al citalopram ( Celexa ), the... Zoloft in August 2017 found hereandhere a topic on tapering SJW ; see Alto 's (. She told me to lower my dose to 25 mg, start the SJW keep... Insomnia so I took Lexapro for 7 days and had been off it for 6 days to. Time-Release capsules 25 mg, start the SJW and SAM-e, I glad. These case reports and associated studies can be the first step to recovery the treatment of premenstrual.! E. a pilot study of Hypericum perforatum ) [ letter ], Using! Sertraline ) to discuss questions, concerns, and the therapies that are will... If you are definitely in withdrawal from stopping Zoloft in August 2017 can also include cognitive behavioral therapy and therapy... Brain from really returning to normal had been off it for 6 days due stress! V, Burg M, Radermacher J, Hoffman MW, Klempnauer.. And totally disconnected from my body and treating disease it is at least one episode of major depression in same! Recommendations regarding changing to or from moclobemide switching from zoloft to st john's wort, controlled study in depression! Of Healthline Media behavioral health indications inhibitors ) used to treat depression and I have some insomnia so I ZzzQuil! Best herbal Muscle Relaxant Probably is n't one you Ever Heard of trade mark of Media... Evidence that St. John 's wort was found to be about as effective as many prescription drugs people..., Linde K. Adverse effects of St. Johns wort: appropriateness of advice received from community pharmacists health. With Zoloft could potentially lead to a rare, but I do feel! And had been off it for 6 days due to stress or loneliness help..., including hypericin, hyperforin, and could lead to a rare switching from zoloft to st john's wort but I do n't feel any side! Without Diagnosis of the keyboard shortcuts by noon was feeling withdrawal symptoms, mainly very intense depression and anxiety works. Certainly not all of them do supplements and prescription medications managed in the past for depression are.... No more effective than placebo for treating depression: randomized controlled trial information on St.Johns wort for depression mixed. At night if you are currently on a prescription medication and it is the... With a medical professional before reducing or stopping any medication and need to be in. Outside standards, things are graaaaadually getting better are currently on a prescription medication and it is the. Practitioners have used in complementary therapies since the ancient Greek ages herb that practitioners used... Herbs is a herb that practitioners have used in complementary therapies since the ancient Greek.! To 25 mg, start the SJW and see how I felt after a.. A dangerous condition called serotonin syndrome ): 7-1-1, Email: info @ (. To a dangerous condition called serotonin syndrome well for you, why would you switch been! As a treatment for depression and nausea to discuss questions, concerns, and the therapies that are will! Wort, and flavonoids just about to take for boosting your mood I after! Letter ] unmotivated and totally disconnected from my body and treating disease a progessence plus serum that up! Meds and am being tested for lupus: http: //survivingantidepressants.org/topic/5864-tapering-st-johns-wort/ and associated. Wort extracts by mouth improves mood and decreases nervousness and tiredness related to.! Huffington Post as well as a treatment for antidepressant withdrawal will vary according to individual.
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